Opportunity Information: Apply for RFA DP 20 002
The grant opportunity titled "Natural Experiments of the Impact of Population-targeted Policies to Prevent Type 2 Diabetes and Diabetes Complications" (RFA DP 20 002) is a CDC cooperative agreement designed to build a coordinated, multi-site research effort focused on real-world policy and program changes that could meaningfully reduce type 2 diabetes risk and diabetes-related complications across US communities. Rather than funding tightly controlled clinical trials, the emphasis is on "natural experiments," meaning evaluations of interventions that are already happening in communities, health systems, or other settings due to policy decisions, program rollouts, or environmental changes. The central idea is to generate stronger, more practical evidence about what works at the population level, especially when communities adopt policies that could shift diet, physical activity, preventive behaviors, or the quality of diabetes care.
The NOFO is organized into two connected components. Component A funds Natural Experiment Research Centers, which together form a 5-year, multi-center network of independent research sites. These centers are expected to design and conduct rigorous evaluations of innovative interventions that influence the "diabetogenic" characteristics of communities, in other words, the local conditions that make it easier for diabetes risk to rise, such as unhealthy food environments, limited opportunities for physical activity, or gaps in prevention and clinical care. Applicants to Component A must choose one of two tracks. Track 1 focuses on evaluating population-level programs or policies that change broad risk factors for type 2 diabetes, including diet, physical activity, other health behaviors, and markers like glucose or prediabetes trends at the community level. Track 2 shifts attention toward programs or policies that improve diabetes care and management, with the goal of reducing the likelihood or severity of complications by improving how people with diabetes are treated, monitored, and supported over time.
Component B funds a Coordinating Center that serves as the operational backbone for the network created under Component A. The Coordinating Center is meant to provide organizational, logistical, and communications support so the separate research centers function like a single, efficient collaborative program rather than isolated projects. In practice, that typically means coordinating meetings and workflows, helping standardize approaches where useful, supporting cross-site learning and shared dissemination, and generally increasing the productivity and public health impact of the studies produced by the research centers. The Coordinating Center role is about making the overall network stronger, faster-moving, and more aligned in terms of outputs and impact.
Administratively, the opportunity is offered by the Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), with applications submitted through the CDC ERA process. It is categorized as a discretionary funding opportunity and uses the cooperative agreement funding instrument, which usually indicates substantial federal involvement during the project period, such as collaboration on priorities, coordination, and expectations for deliverables. The activity category is Health, under CFDA 93.945. The posting was created on November 29, 2019, with an original closing date of February 4, 2020, and the electronic submission deadline set at 5:00 p.m. Eastern Time on the due date.
Eligibility is broad and includes many types of organizations that could credibly lead community- or systems-based research, including state, county, and local governments; special districts; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations (other than small businesses); and small businesses. The listing also notes the opportunity is effectively open to any entity within the eligible categories, subject to any additional clarifications in the full announcement.
In terms of scale, the opportunity lists an award ceiling of $450,000 and anticipates up to 6 awards. Overall, the structure signals a deliberate effort to create a small but coordinated national research network that can evaluate policy and program changes as they occur in real life, producing actionable evidence to guide future decisions about preventing type 2 diabetes and improving outcomes for people already living with the disease.Apply for RFA DP 20 002
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Natural Experiments of the Impact of Population-targeted Policies to Prevent Type 2 Diabetes and Diabetes Complications" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.945.
- This funding opportunity was created on Nov 29, 2019.
- Applicants must submit their applications by Feb 04, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $450,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: Natural Experiments of the Impact of Population-targeted Policies to Prevent Type 2 Diabetes and Diabetes Complications (RFA DP 20 002)
What is the name of this grant opportunity?
The opportunity is titled "Natural Experiments of the Impact of Population-targeted Policies to Prevent Type 2 Diabetes and Diabetes Complications" and is identified as RFA DP 20 002.
Which federal agency is offering this funding?
This is a U.S. Department of Health and Human Services opportunity offered through the Centers for Disease Control and Prevention (CDC).
What type of funding mechanism is this?
The award uses a cooperative agreement funding instrument. This typically means there is substantial federal involvement during the project period, such as collaboration on priorities, coordination activities, and expectations for deliverables.
Is this funding intended for clinical trials?
No. The emphasis is not on tightly controlled clinical trials. Instead, the focus is on "natural experiments", meaning evaluations of real-world interventions already occurring due to policies, program rollouts, or environmental changes in communities, health systems, or other settings.
What is meant by a "natural experiment" in this NOFO?
In this opportunity, a natural experiment refers to research that evaluates interventions that are already happening in real life (for example, changes driven by policy decisions or program implementation), rather than interventions created solely for a controlled research study.
What is the main purpose of the grant?
The purpose is to build a coordinated, multi-site research effort that generates stronger, practical evidence about what works at the population level to:
- Reduce type 2 diabetes risk across U.S. communities, and/or
- Reduce diabetes-related complications by improving diabetes care and management.
What kinds of interventions are of interest?
The NOFO targets evaluations of real-world policy and program changes that could influence population health, including changes that shift:
- Diet and food environments
- Physical activity opportunities
- Preventive behaviors
- Quality of diabetes care and ongoing support
What does "diabetogenic characteristics of communities" mean in this context?
It refers to local conditions that can make diabetes risk more likely to rise, such as unhealthy food environments, limited opportunities for physical activity, or gaps in prevention and clinical care.
How is the NOFO structured?
The NOFO has two connected components:
- Component A: Natural Experiment Research Centers (a 5-year, multi-center network of independent research sites)
- Component B: A Coordinating Center that supports and aligns the network created under Component A
What is Component A?
Component A funds Natural Experiment Research Centers that will form a coordinated, multi-site network for 5 years. These centers are expected to design and conduct rigorous evaluations of innovative interventions that affect community conditions related to diabetes risk or diabetes care.
What are the tracks under Component A?
Applicants to Component A must choose one of two tracks:
- Track 1: Evaluations of population-level programs or policies that change broad risk factors for type 2 diabetes (diet, physical activity, other behaviors, and community-level markers such as glucose or prediabetes trends).
- Track 2: Evaluations of programs or policies that improve diabetes care and management to reduce the likelihood or severity of complications by improving treatment, monitoring, and long-term support for people with diabetes.
What is Component B?
Component B funds a Coordinating Center that serves as the operational backbone of the network. Its role is to ensure the research centers work as a cohesive collaborative program rather than as isolated projects.
What does the Coordinating Center do?
Based on the description provided, the Coordinating Center typically provides:
- Organizational and logistical support for the network
- Coordination of meetings and workflows
- Support for cross-site learning and shared dissemination
- Help standardizing approaches where useful
- Communications support to improve productivity and public health impact
How long is the project period for the research network?
Component A centers are described as forming a 5-year, multi-center network.
What is the CFDA number and activity category?
The opportunity is listed under CFDA 93.945 and the activity category is Health.
Is this a discretionary funding opportunity?
Yes. It is categorized as a discretionary funding opportunity.
How are applications submitted?
Applications are submitted through the CDC ERA process.
When was the opportunity posted?
The posting was created on November 29, 2019.
What was the original closing date?
The original closing date was February 4, 2020.
What time was the electronic submission deadline?
The electronic submission deadline was 5:00 p.m. Eastern Time on the due date.
Who is eligible to apply?
Eligibility is broad and includes the following organization types:
- State, county, and local governments
- Special districts
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized tribal governments and other tribal organizations
- Public housing authorities
- Nonprofits with or without 501(c)(3) status (excluding higher education institutions in those categories)
- For-profit organizations (other than small businesses)
- Small businesses
Is the opportunity limited to certain types of eligible entities?
The listing indicates the opportunity is effectively open to any entity within the eligible categories, subject to any additional clarifications in the full announcement.
How many awards are expected?
The opportunity anticipates up to 6 awards.
What is the maximum award amount (award ceiling)?
The award ceiling listed is $450,000.
What is the overall approach this NOFO is trying to achieve?
The structure is designed to create a small but coordinated national research network that can evaluate policy and program changes as they occur in real-life settings, producing actionable evidence to guide future decisions on preventing type 2 diabetes and improving outcomes for people living with diabetes.
What kinds of outcomes is the NOFO aiming to influence?
The focus is on generating evidence related to reducing type 2 diabetes risk at the population level and reducing diabetes-related complications through improved care, including measures tied to:
- Population-level risk factors (diet, physical activity, behaviors)
- Community-level markers such as glucose or prediabetes trends
- Diabetes treatment, monitoring, and ongoing support that affect complications
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