Opportunity Information: Apply for PAR 25 324

The Method to Extend Research in Time (MERIT) Award Extension Request (R37) from the National Cancer Institute (NCI) is a discretionary NIH grant opportunity designed to give Early Stage Investigators (ESIs) longer-term research support. The central idea is to reduce the pressure ESIs often face to rapidly generate renewal applications and instead provide additional protected time to build a research program, pursue creative and innovative directions, and become more established as independent investigators. This funding opportunity follows NCI guidance referenced in NOT-CA-18-037 and is structured to support eligible investigators for as long as 7 total years, delivered in two segments.

This particular posting is labeled as a "Type 4 eSubmission" and is "Clinical Trial Optional," meaning applicants may propose studies that include clinical trials if appropriate, but a clinical trial is not required. The opportunity is issued by the National Institutes of Health, with the National Cancer Institute as the sponsoring institute, and it sits within NIH health and education-related funding activity categories. It is listed under multiple CFDA numbers (93.393, 93.394, 93.395, 93.396, 93.397, 93.399), reflecting NCI's broad cancer research and related program areas.

Eligibility is broad and includes many standard government, academic, nonprofit, and private-sector entities that can apply for NIH grants. Examples include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (outside of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, non-U.S. (foreign) entities, and applicants located in a U.S. territory or possession.

Key administrative details from the source listing include the Funding Opportunity Number PAR-25-324, with a creation date of 2025-01-06 and an original closing date of 2028-09-07. The listing does not provide an award ceiling or an expected number of awards in the provided fields, so applicants would typically look to the full NIH funding announcement text and related NCI policies for budgeting expectations, allowable costs, and any institute-specific constraints. Overall, the opportunity is best understood as an NCI mechanism to extend the timeline and stability of support for promising ESIs, giving them a longer runway to advance cancer-related research programs and strengthen their long-term career trajectory without the immediate churn of frequent renewal cycles.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.397, 93.399.
  • This funding opportunity was created on 2025-01-06.
  • Applicants must submit their applications by 2028-09-07.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 25 324

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