Opportunity Information: Apply for RFA GH 18 005
The grant opportunity "Enhancing Capacity for Strategic and Applied Research Activities in Support of Control and Elimination of Malaria and Neglected Tropical Diseases" (RFA GH 18 005) is a CDC cooperative agreement designed to strengthen high-impact, real-world research that helps countries improve how they deliver, measure, and refine malaria and neglected tropical disease (NTD) programs. The main aim is not basic lab science, but strategic and applied work that answers practical questions programs face in the field, especially in sub-Saharan Africa, Asia, and Hispaniola. By funding implementation research and evaluation, CDC is looking to generate evidence that can directly improve policy decisions, program performance, and progress toward disease elimination targets.
The announcement is structured around two linked components: Component A focuses on malaria, and Component B focuses on NTDs. For malaria, CDC is emphasizing research that aligns with the WHO Global Technical Strategy for Malaria 2016-2030, with an expectation that projects will produce actionable public health findings. The underlying rationale is that even with major gains in malaria control and elimination over recent years, remaining transmission, operational challenges, and evolving threats mean programs still need better tools, smarter delivery strategies, and stronger measurement systems. In this context, the funded work is meant to support the scale-up of malaria interventions, improve surveillance, and strengthen evaluation so countries can identify what is working, what is not, and what to change to accelerate elimination.
For NTDs, the cooperative agreement supports operational and evaluation research connected to eliminating or controlling multiple parasitic diseases that disproportionately affect underserved populations. CDC highlights its role in providing technical assistance and conducting operational research for onchocerciasis elimination where feasible, elimination of blinding trachoma and lymphatic filariasis as public health problems, and improved control of schistosomiasis and soil-transmitted helminths. The focus is on identifying strategies that make NTD programs more effective at scale, especially by improving how programs deliver interventions and how they track progress through stronger surveillance and evaluation. The intent is to help endemic countries meet elimination and control goals through evidence-driven program improvements rather than isolated pilot efforts.
A key feature of this opportunity is the cooperative agreement mechanism, which generally signals substantial involvement by CDC scientists and staff in technical direction, coordination, and collaboration throughout the project period. The description also situates the funding within CDC's broader global role, including its partnership with the Roll Back Malaria initiative and its status as a WHO Collaborating Center. It further notes CDC's joint implementation role with USAID in the US President's Malaria Initiative, reinforcing that projects funded under this announcement are expected to be closely connected to real program platforms and global strategies, and to complement ongoing international efforts rather than operate in parallel.
Administratively, the opportunity is listed under the Department of Health and Human Services, Centers for Disease Control and Prevention, with CFDA number 93.326 and a health-focused activity category. The award ceiling is $3,000,000, with an anticipated four awards. Eligibility includes nonprofit organizations with 501(c)(3) status (excluding institutions of higher education), nonprofits without 501(c)(3) status (excluding institutions of higher education), and additional eligible entities as noted in the full announcement's eligibility clarification. The funding notice was created on January 11, 2018, with an original application deadline of March 12, 2018, and required electronic submission by 5:00 p.m. Eastern Time on the due date.
Overall, the opportunity is best understood as CDC investing in applied research capacity that helps malaria and NTD programs move from proven interventions to consistently high performance at national scale. The emphasis on implementation research, surveillance, and evaluation reflects a practical goal: generate evidence that quickly translates into better program decisions, better targeting of resources, stronger accountability for results, and measurable acceleration toward control and elimination milestones in endemic regions.Apply for RFA GH 18 005
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Enhancing Capacity for Strategic and Applied Research Activities in Support of Control and Elimination of Malaria and Neglected Tropical Diseases" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.326.
- This funding opportunity was created on Jan 11, 2018.
- Applicants must submit their applications by Mar 12, 2018 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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