Opportunity Information: Apply for RFA CK 20 001
The Enhanced Surveillance and Control of Arboviruses in Puerto Rico funding opportunity (RFA CK 20 001) is a CDC cooperative agreement designed to sustain and expand an ongoing arbovirus research and surveillance platform in a high-risk region of southern Puerto Rico. The program centers on two linked surveillance approaches: a community-based longitudinal cohort that follows residents over time to track arboviral infections, and clinic- and hospital-based surveillance focused on acute febrile illness (AFI). Taken together, these components are meant to provide an early and reliable picture of when and where arboviruses are circulating, how frequently infections are occurring, and what other illnesses may be causing fever in the same communities.
The core intent is continuity plus improvement of existing systems rather than starting from scratch. The project emphasizes strengthening hospital surveillance for AFI so that suspected arboviral cases and other fever-causing infections are recognized and documented more consistently, with better case detection and reporting. In parallel, it supports maintaining an AFI clinical research platform, which functions as an organized way to evaluate patients with fever, collect standardized clinical and epidemiologic information, and support studies that can answer practical questions about diagnosis, risk factors, and outcomes during outbreaks and inter-epidemic periods.
A major element is completing and maintaining a community-based cohort that can be assessed annually. This cohort is used to estimate both incidence (new infections over time) and prevalence (how common infection is at a given point) of arboviral disease, while also measuring the incidence and causes of other acute febrile illnesses in selected communities. That design helps distinguish arboviral trends from other circulating infections that present similarly, and it provides more accurate population-level measures than clinic-based data alone, since not everyone with fever seeks care.
The NOFO also prioritizes building a robust data management system to support the volume and complexity of information generated by community follow-up and clinical surveillance. This includes creating or strengthening systems that can securely capture, manage, and analyze data in a way that supports timely interpretation, quality control, and sharing of findings with appropriate partners. Strong data infrastructure is positioned as essential for turning surveillance into actionable public health insight.
Finally, the opportunity highlights the need for durable partnerships to ensure the program is supported and usable over the long term. Applicants are expected to establish and maintain collaborations with the Puerto Rico local government, community leaders, and other stakeholders. This community and government engagement is framed as necessary for sustained participation in the cohort, effective public health response, and long-term ownership of the surveillance platform beyond the immediate funding period.
Administratively, this is a discretionary cooperative agreement administered by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CFDA 93.084). The posting date was October 17, 2019, with an original application deadline of January 21, 2020 (electronic submissions due by 5:00 p.m. ET). The announcement anticipated a single award, with an award ceiling of $3,000,000. Eligibility is listed broadly as "Others" with additional clarification referenced in the full eligibility section of the announcement.Apply for RFA CK 20 001
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Enhanced Surveillance and Control of Arboviruses in Puerto Rico" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on Oct 17, 2019.
- Applicants must submit their applications by Jan 21, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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