AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) | PAR 24 165

Opportunity Information: Apply for PAR 24 165

The AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional), funding opportunity number PAR-24-165, is a National Institutes of Health (NIH) grant run by the National Institute of Mental Health (NIMH) Division of AIDS Research (DAR). It supports the creation or strengthening of HIV/AIDS Research Centers (ARCs) through the P30 "Center Core" mechanism, which is designed to fund shared infrastructure rather than a single stand-alone research project. The central goal is to build and sustain the organizational capacity, shared resources, and scientific environment needed to accelerate high-impact research at the intersection of HIV/AIDS and mental health, in ways that align with the NIMH mission.

This opportunity emphasizes innovative and interdisciplinary science and is intentionally broad in the kinds of HIV and mental health research it aims to enable. Centers supported under this program can span basic research, NeuroHIV (including nervous system and brain-related aspects of HIV), behavioral and social science, integrated biobehavioral approaches, applied and clinical research, translational work that moves discoveries toward practice, and implementation science focused on real-world delivery and uptake of effective interventions. The "clinical trial optional" designation means applicants may propose activities that include clinical trials if appropriate for the center, but proposing a trial is not required to be competitive; the focus is on infrastructure that supports a robust, collaborative research portfolio.

Eligible applicants are wide-ranging and include many types of U.S.-based organizations and governments. Examples listed include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; and small businesses. The NOFO also highlights eligibility for several institution types and community-oriented entities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the solicitation is explicit about restrictions related to foreign involvement. Non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed. In practice, that means the applicant organization and the proposed center infrastructure must be firmly based in the United States and cannot rely on formal foreign components as part of the funded structure.

The award is categorized as discretionary funding and uses the grant funding instrument, with an activity category in health and a CFDA number of 93.242. The original closing date is listed as August 25, 2026. While the provided source text does not specify an award ceiling or the expected number of awards, the intent is clear: to fund core resources and shared services that make an ARC more effective, more collaborative, and better positioned to generate impactful HIV/AIDS and mental health science across multiple disciplines and stages of research, from mechanistic work through implementation in real-world settings.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
• This funding opportunity was created on 2024-03-22.
• Applicants must submit their applications by 2026-08-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 24 165

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