Opportunity Information: Apply for PA 17 042

The National Institutes of Health (NIH) funding opportunity titled "Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R21)" (Funding Opportunity Number PA 17 042) is a discretionary grant mechanism designed to support early-stage, innovative research focused on immigrant health in the United States. It uses the NIH R21 format, which is typically intended for exploratory and developmental studies that test new ideas, generate preliminary evidence, or open up promising new lines of inquiry rather than delivering large-scale definitive trials. The central aim of this FOA is to improve understanding of the underlying causes (the etiology) of both poorer health outcomes (health disparities) and better-than-expected outcomes (health advantages) observed in U.S. immigrant populations.

The scientific focus is broad and intentionally multidisciplinary. NIH is looking for projects that examine uniquely associated factors shaping immigrant health, including biological influences, behavioral patterns, sociocultural conditions, and environmental contexts. In practical terms, this could include research on how migration-related stress, discrimination, language barriers, legal status concerns, work conditions, neighborhood exposures, or access to culturally appropriate care might contribute to health risks. It also includes research that explains why some immigrant groups show health advantages, such as lower rates of certain chronic conditions upon arrival, strong social cohesion, protective cultural practices, or healthier baseline behaviors, and how those advantages may change over time or across generations. The exploratory nature of the R21 mechanism makes it well-suited for developing new measurement approaches, piloting community-engaged methods, testing novel hypotheses about pathways linking immigration experiences to health, or identifying mechanisms that can later be targeted by interventions.

Eligibility under this announcement is expansive and includes a wide range of U.S.-based organizations. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; and Native American tribal organizations that are not federally recognized tribal governments. Nonprofit organizations are eligible whether or not they have 501(c)(3) status, as are for-profit organizations (other than small businesses) and small businesses. The FOA also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, tribal governments other than federally recognized ones, and U.S. territories or possessions. This broad eligibility reflects the reality that immigrant health research often benefits from partnerships across academia, community organizations, public agencies, and service systems.

There are important limits related to foreign involvement. Non-domestic (non-U.S.) entities and non-domestic institutions are not eligible to apply as the applicant organization. In addition, non-domestic components of U.S. organizations are not eligible to apply. However, the FOA allows foreign components as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain foreign elements in the project when scientifically justified and compliant with NIH policy, even though a foreign institution cannot serve as the primary applicant.

From the funding details provided, the award ceiling is listed as $200,000, indicating the maximum level of support anticipated under this opportunity as presented in the source data. The activity aligns with NIH program areas spanning education, environment, and health, and the opportunity is associated with multiple CFDA numbers: 93.113, 93.121, 93.273, 93.279, 93.307, 93.396, and 93.399. The FOA was created on 2016-11-01, and the original closing date shown in the source data is 2020-01-07.

Overall, this grant opportunity is aimed at generating fresh, mechanistic insights into why immigrant populations experience specific patterns of health risk and resilience in the U.S. context, with a strong emphasis on innovative, early-stage studies that can build the foundation for larger research programs and, eventually, more targeted strategies to reduce disparities while preserving or understanding health advantages.

  • The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.273, 93.279, 93.307, 93.396, 93.399.
  • This funding opportunity was created on 2016-11-01.
  • Applicants must submit their applications by 2020-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Funding Opportunity
Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21) Apply for PA 17 044

Funding Number: PA 17 044
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Expanding Genome Integrity Assays to Population Studies (U01) Apply for RFA ES 17 006

Funding Number: RFA ES 17 006
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Ethical, Legal, and Social Implications (ELSI) of Genomics Small Research Grant Program (R03) Apply for PA 17 324

Funding Number: PA 17 324
Agency: National Institutes of Health
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Ethical, Legal, and Social Implications (ELSI) of Genomics Exploratory/Developmental Research Grant Program (R21) Apply for PA 17 323

Funding Number: PA 17 323
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $275,000
Ethical, Legal, and Social Implications (ELSI) of Genomics Research Project Grant Program (R01) Apply for PA 17 325

Funding Number: PA 17 325
Agency: National Institutes of Health
Category: Education, Environment, Health
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Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP) - U.S. Entity (Admin Supplement) Apply for PA 17 326

Funding Number: PA 17 326
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) Apply for PAR 17 476

Funding Number: PAR 17 476
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R21 - Clinical Trial Not Allowed) Apply for PAR 17 475

Funding Number: PAR 17 475
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Collaborative Minority Health and Health Disparities Research with Tribal Epidemiology Centers (R01) Apply for PAR 17 484

Funding Number: PAR 17 484
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $350,000
Collaborative Minority Health and Health Disparities Research with Tribal Epidemiology Centers (R21) Apply for PAR 17 483

Funding Number: PAR 17 483
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Research to Improve Native American Health (R21 Clinical Trial Optional) Apply for PAR 17 464

Funding Number: PAR 17 464
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) Apply for PAR 17 496

Funding Number: PAR 17 496
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R01 Clinical Trial Optional) Apply for PA 18 284

Funding Number: PA 18 284
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21 Clinical Trial Optional) Apply for PA 18 285

Funding Number: PA 18 285
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
NIH Research Project Grant (Parent R01 Clinical Trial Required) Apply for PA 18 345

Funding Number: PA 18 345
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional) Apply for PA 18 260

Funding Number: PA 18 260
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) Apply for PA 18 344

Funding Number: PA 18 344
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21 Clinical Trial Optional) Apply for PA 18 160

Funding Number: PA 18 160
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: $200,000
Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01 Clinical Trial Optional) Apply for PA 18 142

Funding Number: PA 18 142
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent
Independent Scientist Award (Parent K02 - Independent Clinical Trials Not Allowed) Apply for PA 18 371

Funding Number: PA 18 371
Agency: National Institutes of Health
Category: Education, Environment, Health
Funding Amount: Case Dependent

 

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